|
KMID : 0369319930130030296
|
|
Allergy
1993 Volume.13 No. 3 p.296 ~ p.301
|
|
|
the Reversibility of Ventilatory Function in Acute Exacerbation and Recovery of Childhood Asthma
|
|
윤경철
최대영/안호식/김성원
|
|
|
Abstract
|
|
|
Pulmonary function testing is valuable in assessing the degree of airway obstruction and the disturbance in gas exchange, in measuring response of the airways to inhaled allergens or exercise, in assessing the response to therapeutic agents, and
in
evaluating the long-term course of the disease.
Assessments of pulmonary function in asthma are most valuable when made before and after administration of an aerosol bronchodilator, a procedure that indicates the degree of reversibility of the airway obstruction at the time of the testing.
In order to estimate the reversibility of ventilatory functions in acute exacerbation and recovery of childhood asthma, spirometric measurements before and after salbutamlol inhalation were performed on 32 children with acute exacerbation of
asthma, age
ranging from 6 to 15 years, who had been admitted to the Department of Pediatrics, Saint Benedict Hospital from February, 1991 to January, 1992.
@ES The results were as follows:
@EN 1) During acute exacerbation, all parameters except FEV1% after salbutamol inhalation significantly increased than those before inhalation, while at discharge, all parameters after inhalation significantly increased than those before
inhalation.
2) The percent change[(value measured after inhalation-value measured before inhalation)÷value measured before inhalation] of the parameters such as PEFR and FEV1 which are affected more by alterations in the large airways were significantly
higher in
acute exacerbation than at discharge, while the percent change of the parameters such as MMF, FEF50, and FEF75 which reflect alterations in the small airways were significantly higher at discharge than in acute exacerbation.
In conclusion, significant increment of the percent change of the parameters such as FEF75, FEF50, and MMF would be regarded as the indicator of recovery from acute exacerbation of asthma.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|